IFabdInterferon alpha, beta and delta. |
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| SMART accession number: | SM00076 |
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| Description: | Interferons produce antiviral and antiproliferative responses in cells. They are classified into five groups, all of them related but gamma-interferon. |
| Interpro abstract (IPR000471): | Interferons [(PUBMED:3022999)] are proteins which produce antiviral and antiproliferative responses in cells. On the basis of their sequence interferons are classified into five groups: alpha, alpha-II (or omega), beta, delta (or trophoblast). The sequence differences may possibly cause different responses to various inducers, or result in the recognition of different target cell types [(PUBMED:6170983)]. The main conserved structural feature of interferons is a disulphide bond that, except in mouse beta interferon, occurs in all alpha, beta and omega sequences. |
| GO process: | defense response (GO:0006952) |
| GO component: | extracellular region (GO:0005576) |
| GO function: | cytokine receptor binding (GO:0005126) |
| Family alignment: |
There are 389 IFabd domains in 389 proteins in SMART's nrdb database.
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- Evolution (species in which this domain is found)
- Metabolism (metabolic pathways involving proteins which contain this domain)
- Structure (3D structures containing this domain)
- Links (links to other resources describing this domain)
to expand nodes. To display all proteins with a IFabd domain in a specific node, click on it.
