Interleukins 4 and 13
SMART accession number:SM00190
Description: Interleukins-4 and -13 are cytokines involved in inflammatory and immune responses. IL-4 stimulates B and T cells.
Interpro abstract (IPR001325):

Interleukin-4 (IL-4) is a cytokine that plays a central role in the control and regulation of the immune and inflammatory system [ (PUBMED:3284813) (PUBMED:1693082) ]. IL-4 is a participant in several B-cell activation processes. It also stimulates other cell types such as T cells or mast cells. IL-4 is a glycoprotein that contains three disulphide bonds [ (PUBMED:1993171) ].

Interleukin-13 (IL-13) is a pleiotropic cytokine which may be important in the regulation of the inflammatory and immune responses [ (PUBMED:8096327) ]. The sequences of IL-4 and IL-13 are distantly related. This entry represetns both IL-4 and IL-13.

GO process:immune response (GO:0006955)
GO component:extracellular region (GO:0005576)
GO function:cytokine receptor binding (GO:0005126)
Family alignment:
View or

There are 277 IL4_13 domains in 277 proteins in SMART's nrdb database.

Click on the following links for more information.