MA3Domain in DAP-5, eIF4G, MA-3 and other proteins.
|SMART accession number:||SM00544|
|Description:||Highly alpha-helical. May contain repeats and/or regions similar to MIF4G domains Ponting (TIBS) "Novel eIF4G domain homologues" in press|
|Interpro abstract (IPR003891):|
This entry represents the MI domain (after MA-3 and eIF4G), it is a protein-protein interaction module of ~130 amino acids [(PUBMED:10958635), (PUBMED:10973054), (PUBMED:15082783)]. It appears in several translation factors and is found in:
The MI domain consists of seven alpha-helices, which pack into a globular form. The packing arrangement consists of repeating pairs of antiparallel helices packed one upon the other such that a superhelical axis is generated perpendicular to the alpha-helical axes [(PUBMED:17060447)].
The MI domain has also been named MA3 domain.
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- Evolution (species in which this domain is found)
- Literature (relevant references for this domain)
- Structure (3D structures containing this domain)
- Links (links to other resources describing this domain)