Med12Transcription mediator complex subunit Med12
|SMART accession number:||SM01281
||Med12 is a negative regulator of the Gli3-dependent sonic hedgehog signalling pathway via its interaction with Gli3 within the RNA polymerase II transcriptional Mediator. A complex is formed between Med12, Med13, CDK8 and CycC which is responsible for suppression of transcription. This subunit forms part of the Kinase section of Mediator PMID:15175151.|
There are 0 Med12 domains in 0 proteins in SMART's nrdb database.
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Cellular role (predicted cellular role)
Literature (relevant references for this domain)
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