MutL_C

MutL C terminal dimerisation domain
MutL_C
SMART accession number:SM00853
Description: MutL and MutS are key components of the DNA repair machinery that corrects replication errors. MutS recognises mispaired or unpaired bases in a DNA duplex and in the presence of ATP, recruits MutL to form a DNA signaling complex for repair. The N terminal region of MutL contains the ATPase domain and the C terminal is involved in dimerisation.
Interpro abstract (IPR014790):

MutL and MutS are key components of the DNA repair machinery that corrects replication errors [(PUBMED:8811176)]. MutS recognises mispaired or unpaired bases in a DNA duplex and in the presence of ATP, recruits MutL to form a DNA signalling complex for repair. The N-terminal region of MutL contains the ATPase domain and the C-terminal is involved in dimerisation [(PUBMED:15470502)].

GO process:mismatch repair (GO:0006298)
GO function:ATP binding (GO:0005524)
Family alignment:
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There are 1808 MutL_C domains in 1808 proteins in SMART's nrdb database.

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