N-SET

COMPASS (Complex proteins associated with Set1p) component N
N-SET
SMART accession number:SM01291
Description: The n-SET or N-SET domain is a component of the COMPASS complex, associated with SET1, conserved in yeasts and in other eukaryotes up to humans. The COMPASS complex functions to methylate the fourth lysine of Histone 3 and for the silencing of genes close to the telomeres of chromosomes PMID:11805083. This domain promotes trimethylation in conjunction with an RRM domain PMID:15775977and is necessary for binding of the Spp1 component of COMPASS into the complex PMID:16921172.
Family alignment:
View or

There are 0 N-SET domains in 0 proteins in SMART's nrdb database.

Click on the following links for more information.

  • Links (links to other resources describing this domain)