PAWdomain present in PNGases and other hypothetical proteins
|SMART accession number:||SM00613|
|Description:||present in several copies in proteins with unknown function in C. elegans|
|Interpro abstract (IPR006588):|
The PAW domain (present in PNGases and other worm proteins) is found as a single copy at the C terminus of metazoan peptide:N-glycanase (PNGase) and in multiple copies in hypothetical Caenorhabditis elegans proteins peptide:N-glycanases (PNGases) [(PUBMED:11779830)]. The C-terminal PAW domain of PNGase binds to the mannose moieties of N-linked oligosaccharide chains [(PUBMED:17088551)].
The PAW domain is a slightly elongated molecule and displays a beta-sandwich architecture, which is composed of two layers, containing nine and eight antiparallel beta-strands, respectively, and three additional short helices [(PUBMED:17088551)].
Some proteins known to contain a PAW domain are listed below:
|GO process:||glycoprotein catabolic process (GO:0006516)|
|GO component:||cytoplasm (GO:0005737)|
Click on the following links for more information.
- Evolution (species in which this domain is found)
- Literature (relevant references for this domain)
- Structure (3D structures containing this domain)
- Links (links to other resources describing this domain)