PKS_KR

PKS_KR
SMART accession number:SM00822
Description: This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group.
Interpro abstract (IPR013968):

This domain is found in polyketide and fatty acid synthases that catalyse the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group [(PUBMED:23790488)].

Family alignment:
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There are 9814 PKS_KR domains in 7352 proteins in SMART's nrdb database.

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