POLXcDNA polymerase X family |
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SMART accession number: | SM00483 |
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Description: | includes vertebrate polymerase beta and terminal deoxynucleotidyltransferases |
Interpro abstract (IPR002054): | DNA carries the biological information that instructs cells how to exist in an ordered fashion: accurate replication is thus one of the most important events in the cell life cycle. This function is mediated by DNA-directed DNA-polymerases, which add nucleotide triphosphate (dNTP) residues to the 5'-end of the growing DNA chain, using a complementary DNA as template. Small RNA molecules are generally used as primers for chain elongation, although terminal proteins may also be used. Three motifs, A, B and C [ (PUBMED:2196557) ], are seen to be conserved across all DNA-polymerases, with motifs A and C also seen in RNA- polymerases. They are centred on invariant residues, and their structural significance was implied from the Klenow (Escherichia coli) structure: motif A contains a strictly-conserved aspartate at the junction of a beta-strand and an alpha-helix; motif B contains an alpha-helix with positive charges; and motif C has a doublet of negative charges, located in a beta-turn-beta secondary structure [ (PUBMED:2196557) ]. DNA polymerases ( EC 2.7.7.7 ) can be classified, on the basis of sequence similarity [ (PUBMED:3479792) (PUBMED:2196557) ], into at least four different groups: A, B, C and X. X family polymerases fill in short gaps during DNA repair, and are small (about 40kDa) compared with other polymerases. They are relatively inaccurate enzymes and play roles in base excision repair, in non-homologous end joining (NHEJ) which acts mainly to repair damage due to ionizing radiation, and in V(D)J recombination [ (PUBMED:16061182) (PUBMED:15100289) ]. X family polymerases include eukaryotic Pol beta, Pol lambda, Pol mu and terminal deoxynucleotidyl-transferase (TdT) ( EC 2.7.7.31 ). Pol beta and Pol lambda are primarily DNA template-dependent polymerases, whereas TdT is a DNA template-independent polymerase [ (PUBMED:18972388) ]. Pol mu has both template dependent and template independent activities [ (PUBMED:17159995) ]. These enzymes catalyse addition of nucleotides in a distributive manner, i.e. they dissociate from the template-primer after addition of each nucleotide. DNA-polymerases show a degree of structural similarity with RNA-polymerases. This domain is found either at the extreme N or C termini of DNA polymerase X proteins. |
GO function: | DNA-directed DNA polymerase activity (GO:0003887), DNA binding (GO:0003677) |
Family alignment: |
There are 6622 POLXc domains in 6621 proteins in SMART's nrdb database.
Click on the following links for more information.
- Evolution (species in which this domain is found)
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Taxonomic distribution of proteins containing POLXc domain.
This tree includes only several representative species. The complete taxonomic breakdown of all proteins with POLXc domain is also avaliable.
Click on the protein counts, or double click on taxonomic names to display all proteins containing POLXc domain in the selected taxonomic class.
- Literature (relevant references for this domain)
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Primary literature is listed below; Automatically-derived, secondary literature is also avaliable.
- Pelletier H, Sawaya MR, Kumar A, Wilson SH, Kraut J
- Structures of ternary complexes of rat DNA polymerase beta, a DNA template-primer, and ddCTP.
- Science. 1994; 264: 1891-903
- Display abstract
Two ternary complexes of rat DNA polymerase beta (pol beta), a DNA template-primer, and dideoxycytidine triphosphate (ddCTP) have been determined at 2.9 A and 3.6 A resolution, respectively. ddCTP is the triphosphate of dideoxycytidine (ddC), a nucleoside analog that targets the reverse transcriptase of human immunodeficiency virus (HIV) and is at present used to treat AIDS. Although crystals of the two complexes belong to different space groups, the structures are similar, suggesting that the polymerase-DNA-ddCTP interactions are not affected by crystal packing forces. In the pol beta active site, the attacking 3'-OH of the elongating primer, the ddCTP phosphates, and two Mg2+ ions are all clustered around Asp190, Asp192, and Asp256. Two of these residues, Asp190 and Asp256, are present in the amino acid sequences of all polymerases so far studied and are also spatially similar in the four polymerases--the Klenow fragment of Escherichia coli DNA polymerase I, HIV-1 reverse transcriptase, T7 RNA polymerase, and rat DNA pol beta--whose crystal structures are now known. A two-metal ion mechanism is described for the nucleotidyl transfer reaction and may apply to all polymerases. In the ternary complex structures analyzed, pol beta binds to the DNA template-primer in a different manner from that recently proposed for other polymerase-DNA models.
- Metabolism (metabolic pathways involving proteins which contain this domain)
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% proteins involved KEGG pathway ID Description 100.00 map04640 Hematopoietic cell lineage This information is based on mapping of SMART genomic protein database to KEGG orthologous groups. Percentage points are related to the number of proteins with POLXc domain which could be assigned to a KEGG orthologous group, and not all proteins containing POLXc domain. Please note that proteins can be included in multiple pathways, ie. the numbers above will not always add up to 100%.
- Structure (3D structures containing this domain)
3D Structures of POLXc domains in PDB
PDB code Main view Title 1bpb CRYSTAL STRUCTURE OF RAT DNA POLYMERASE BETA: EVIDENCE FOR A COMMON POLYMERASE MECHANISM 1bpd CRYSTAL STRUCTURE OF RAT DNA POLYMERASE BETA: EVIDENCE FOR A COMMON POLYMERASE MECHANISM 1bpe CRYSTAL STRUCTURE OF RAT DNA POLYMERASE BETA; EVIDENCE FOR A COMMON POLYMERASE MECHANISM 1bpx DNA POLYMERASE BETA/DNA COMPLEX 1bpy HUMAN DNA POLYMERASE BETA COMPLEXED WITH GAPPED DNA AND DDCTP 1bpz HUMAN DNA POLYMERASE BETA COMPLEXED WITH NICKED DNA 1huo CRYSTAL STRUCTURE OF DNA POLYMERASE BETA COMPLEXED WITH DNA AND CR-TMPPCP 1huz CRYSTAL STRUCTURE OF DNA POLYMERASE COMPLEXED WITH DNA AND CR-PCP 1jms Crystal Structure of the Catalytic Core of Murine Terminal Deoxynucleotidyl Transferase 1jn3 FIDELITY PROPERTIES AND STRUCTURE OF M282L MUTATOR MUTANT OF DNA POLYMERASE: SUBTLE STRUCTURAL CHANGES INFLUENCE THE MECHANISM OF NUCLEOTIDE DISCRIMINATION 1kdh Binary Complex of Murine Terminal Deoxynucleotidyl Transferase with a Primer Single Stranded DNA 1kej Crystal Structure of Murine Terminal Deoxynucleotidyl Transferase complexed with ddATP 1mq2 Human DNA Polymerase Beta Complexed With Gapped DNA Containing an 8-oxo-7,8-dihydro-Guanine and dAMP 1mq3 Human DNA Polymerase Beta Complexed With Gapped DNA Containing an 8-oxo-7,8-dihydro-Guanine Template Paired with dCTP 1nom DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7), 31-KD DOMAIN; SOAKED IN THE PRESENCE OF MNCL2 (5 MILLIMOLAR) 1rpl 2.3 ANGSTROMS CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF DNA POLYMERASE BETA 1rzt Crystal structure of DNA polymerase lambda complexed with a two nucleotide gap DNA molecule 1tv9 HUMAN DNA POLYMERASE BETA COMPLEXED WITH NICKED DNA CONTAINING A MISMATCHED TEMPLATE ADENINE AND INCOMING CYTIDINE 1tva HUMAN DNA POLYMERASE BETA COMPLEXED WITH NICKED DNA CONTAINING A MISMATCHED TEMPLATE THYMIDINE AND INCOMING CYTIDINE 1xsl Crystal Structure of human DNA polymerase lambda in complex with a one nucleotide DNA gap 1xsn Crystal Structure of human DNA polymerase lambda in complex with a one nucleotide DNA gap and ddTTP 1xsp Crystal Structure of human DNA polymerase lambda in complex with nicked DNA and pyrophosphate 1zjm Human DNA Polymerase beta complexed with DNA containing an A-A mismatched primer terminus 1zjn Human DNA Polymerase beta complexed with DNA containing an A-A mismatched primer terminus with dGTP 1zqa DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF KCL (150 MILLIMOLAR) AT PH 7.5 1zqb DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF BACL2 (150 MILLIMOLAR) 1zqc DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF CACL2 (15 MILLIMOLAR) 1zqd DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF CACL2 (150 MILLIMOLAR) 1zqe DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF CRCL3 (SATURATED SOLUTION) 1zqf DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF CSCL (150 MILLIMOLAR) 1zqg DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF A SODIUM-FREE ARTIFICIAL MOTHER LIQUOR AT PH 6.5 1zqh DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF A SODIUM-FREE ARTIFICIAL MOTHER LIQUOR AT PH 7.5 1zqi DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF KCL (150 MILLIMOLAR) 1zqj DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF CACL2 (15 MILLIMOLAR) AND MGCL2 (15 MILLIMOLAR) 1zqk DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF KCL (75 MILLIMOLAR) AND MGCL2 (75 MILLIMOLAR) 1zql DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF MNCL2 (15 MILLIMOLAR) AND MGCL2 (15 MILLIMOLAR) 1zqm DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF MNCL2 (15 MILLIMOLAR) 1zqn DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF BACL2 (15 MILLIMOLAR) AND NACL (15 MILLIMOLAR) 1zqo DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF CACL2 (15 MILLIMOLAR) AND NACL (15 MILLIMOLAR) 1zqp DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF KCL (75 MILLIMOLAR) AND NACL (75 MILLIMOLAR) 1zqq DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF MNCL2 (15 MILLIMOLAR) AND NACL (15 MILLIMOLAR) 1zqr DNA POLYMERASE BETA (E.C.2.7.7.7)/DNA COMPLEX, SOAKED IN THE PRESENCE OF NICL2 1zqs DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF TLCL (0.5 MILLIMOLAR) 1zqt DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF DATP (0.01 MILLIMOLAR) AND ZNCL2 (0.02 MILLIMOLAR) 1zqu DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7), 31-KD DOMAIN; SOAKED IN THE PRESENCE OF ARTIFICIAL MOTHER LIQUOR 1zqv DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7), 31-KD DOMAIN; SOAKED IN THE PRESENCE OF CACL2 (150 MILLIMOLAR) 1zqw DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7), 31-KD DOMAIN; SOAKED IN THE PRESENCE OF CSCL (150 MILLIMOLAR) 1zqx DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7), 31-KD DOMAIN; SOAKED IN THE PRESENCE OF KCL (150 MILLIMOLAR) 1zqy DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7), 31-KD DOMAIN; SOAKED IN THE PRESENCE OF MGCL2 (50 MILLIMOLAR) 1zqz DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7), 31-KD DOMAIN; SOAKED IN THE PRESENCE OF MNCL2 (50 MILLIMOLAR) 2bcq DNA polymerase lambda in complex with a DNA duplex containing an unpaired Dtmp 2bcr DNA polymerase lambda in complex with a DNA duplex containing an unpaired Damp 2bcs DNA polymerase lambda in complex with a DNA duplex containing an unpaired Dcmp 2bcu DNA polymerase lambda in complex with a DNA duplex containing an unpaired Damp and a T:T mismatch 2bcv DNA polymerase lambda in complex with Dttp and a DNA duplex containing an unpaired Dtmp 2bpc CRYSTAL STRUCTURE OF RAT DNA POLYMERASE BETA: EVIDENCE FOR A COMMON POLYMERASE MECHANISM 2bpf STRUCTURES OF TERNARY COMPLEXES OF RAT DNA POLYMERASE BETA, A DNA TEMPLATE-PRIMER, AND DDCTP 2bpg STRUCTURES OF TERNARY COMPLEXES OF RAT DNA POLYMERASE BETA, A DNA TEMPLATE-PRIMER, AND DDCTP 2fmp DNA Polymerase beta with a terminated gapped DNA substrate and ddCTP with sodium in the catalytic site 2fmq Sodium in active site of DNA Polymerase Beta 2fms DNA Polymerase beta with a gapped DNA substrate and dUMPNPP with magnesium in the catalytic site 2gws Crystal Structure of human DNA Polymerase lambda with a G/G mismatch in the primer terminus 2i9g DNA Polymerase Beta with a Benzo[c]phenanthrene diol epoxide adducted guanine base 2ihm Polymerase mu in ternary complex with gapped 11mer DNA duplex and bound incoming nucleotide 2iso Ternary complex of DNA Polymerase beta with a dideoxy terminated primer and 2'-deoxyguanosine 5'-beta, gamma-difluoromethylene triphosphate 2isp Ternary complex of DNA Polymerase beta with a dideoxy terminated primer and 2'-deoxyguanosine 5'-beta, gamma-methylene triphosphate 2p66 Human DNA Polymerase beta complexed with tetrahydrofuran (abasic site) containing DNA 2pfn Na in the active site of DNA Polymerase lambda 2pfo DNA Polymerase lambda in complex with DNA and dUPNPP 2pfp DNA Polymerase lambda in complex with DNA and dCTP 2pfq Manganese promotes catalysis in a DNA polymerase lambda-DNA crystal 2pxi Ternary complex of DNA polymerase beta with a dideoxy terminated primer and 2'-deoxyguanosine 5'-beta, gamma-monofluoromethylene triphosphate 2van Crystal structure of DNA polymerase beta 2w9m Structure of family X DNA polymerase from Deinococcus radiodurans 3au2 DNA polymerase X from Thermus thermophilus HB8 complexed with Ca-dGTP 3au6 DNA polymerase X from Thermus thermophilus HB8 ternary complex with primer/template DNA and ddGTP 3auo DNA polymerase X from Thermus thermophilus HB8 ternary complex with 1-nt gapped DNA and ddGTP 3b0x K263A mutant of PolX from Thermus thermophilus HB8 complexed with Ca-dGTP 3b0y K263D mutant of PolX from Thermus thermophilus HB8 complexed with Ca-dGTP 3c2k DNA POLYMERASE BETA with a gapped DNA substrate and DUMPNPP with Manganese in the active site 3c2l Ternary complex of DNA POLYMERASE BETA with a C:DAPCPP mismatch in the active site 3c2m Ternary complex of DNA POLYMERASE BETA with a G:dAPCPP mismatch in the active site 3c5f Structure of a binary complex of the R517A Pol lambda mutant 3c5g Structure of a ternary complex of the R517K Pol lambda mutant 3gdx Dna polymerase beta with a gapped DND substrate and dTMP(CF2)PP 3hw8 ternary complex of DNA polymerase lambda of a two nucleotide gapped DNA substrate with a C in the scrunch site 3hwt Ternary complex of DNA polymerase lambda bound to a two nucleotide gapped DNA substrate with a scrunched dA 3hx0 ternary complex of L277A, H511A, R514 mutant pol lambda bound to a 2 nucleotide gapped DNA substrate with a scrunched dA 3isb Binary complex of human DNA polymerase beta with a gapped DNA 3isc Binary complex of human DNA polymerase beta with an abasic site (THF) in the gapped DNA 3isd Ternary complex of human DNA polymerase beta with an abasic site (THF): DAPCPP mismatch 3jpn Ternary complex of DNA polymerase beta with a dideoxy terminated primer and 2'-deoxyguanosine 5'-beta, gamma-dichloro methylene triphosphate 3jpo Ternary complex of DNA polymerase beta with a dideoxy terminated primer and 2'-deoxyguanosine 5'-beta, gamma-monochloromethylene triphosphate 3jpp Ternary complex of DNA polymerase beta with a dideoxy terminated primer and 2'-deoxyguanosine 5'-beta, gamma-MonoMethyl Methylene triphosphate 3jpq Ternary complex of DNA polymerase beta with a dideoxy terminated primer and 2'-deoxyguanosine 5'-beta, gamma-monoBromo methylene triphosphate 3jpr Ternary complex of DNA polymerase beta with a dideoxy terminated primer and 2'-deoxyguanosine 5'-beta, gamma-dimethyl methylene triphosphate 3jps Ternary complex of DNA polymerase beta with a dideoxy terminated primer and 2'-deoxyguanosine 5'-beta, gamma-fluoro methyl methylene triphosphate 3jpt Ternary complex of DNA polymerase beta with a dideoxy terminated primer and 2'-deoxyguanosine 5'-beta, gamma-fluoro chloro methylene triphosphate 3k75 X-ray crystal structure of reduced XRCC1 bound to DNA pol beta catalytic domain 3lk9 DNA polymerase beta with a gapped DNA substrate and dTMP(CF2)P(CF2)P 3lqc X-ray crystal structure of oxidized XRCC1 bound to DNA pol beta Palm thumb domain 3mby Ternary complex of DNA Polymerase BETA with template base A and 8oxodGTP in the active site with a dideoxy terminated primer 3mda DNA polymerase lambda in complex with araC 3mdc DNA polymerase lambda in complex with dFdCTP 3mgh Binary complex of a DNA polymerase lambda loop mutant 3mgi Ternary complex of a DNA polymerase lambda loop mutant 3ogu DNA Polymerase beta mutant 5P20 complexed with 6bp of DNA 3pml crystal structure of a polymerase lambda variant with a dGTP analog opposite a templating T 3pmn ternary crystal structure of polymerase lambda variant with a GT mispair at the primer terminus with Mn2+ in the active site 3pnc Ternary crystal structure of a polymerase lambda variant with a GT mispair at the primer terminus and sodium at catalytic metal site 3rh4 DNA Polymerase Beta with a dideoxy-terminated primer with an incoming ribonucleotide (rCTP) 3rh5 DNA Polymerase Beta Mutant (Y271) with a dideoxy-terminated primer with an incoming deoxynucleotide (dCTP) 3rh6 DNA Polymerase Beta Mutant (Y271) with a dideoxy-terminated primer with an incoming ribonucleotide (rCTP) 3rje Ternary complex of DNA Polymerase Beta with a gapped DNA containing 8odG at template position 3rjf Ternary complex of DNA Polymerase Beta with a gapped DNA containing (syn)8odG at template position paired with non-hydrolyzable dATP analog (dApCPP) 3rjg Binary complex of DNA Polymerase Beta with a gapped DNA containing 8odG:dA base-pair at primer Terminus 3rjh Ternary complex of DNA Polymerase Beta with a gapped DNA containing (syn)8odG:dA at primer terminus and dG:dCMP(CF2)PPin the active site 3rji Ternary complex of DNA Polymerase Beta with a gapped DNA containing 8odG at template position paired with non-hydrolyzable dCTP analog (dCMP(CF2)PP) 3rjj Ternary complex crystal structure of DNA Polymerase Beta with template 8odG provides insight into mutagenic lesion bypass 3rjk Ternary complex of DNA Polymerase Beta with a gapped DNA containing 8odG:dC base pair at primer terminus and dG:dCMP(CF2)PP in the active site 3tfr Ternary complex structure of DNA polymerase beta with a gapped DNA substrate and a, b dAMP(CF2)PP in the active site 3tfs Ternary complex structure of DNA polymerase beta with a gapped DNA substrate and a, b dAMP(CFH)PP in the active site: Stereoselective binding of (S) isomer 3upq Crystal structure of the pre-catalytic ternary complex of polymerase lambda with an rATP analog opposite a templating T. 3uq0 Crystal structure of the post-catalytic product complex of polymerase lambda with an rAMP at the primer terminus. 3uq2 Crystal structure of the post-catalytic product complex of polymerase lambda with an rCMP inserted opposite a templating G and dAMP inserted opposite a templating T at the primer terminus. 3uxn Crystal Structure of Rat DNA Polymerase Beta, Wild Type Apoenzyme 3uxo Crystal Structure of Rat DNA Polymerase Beta Mutator I260Q Apoenzyme 3uxp Co-crystal Structure of Rat DNA polymerase beta Mutator I260Q: Enzyme-DNA-ddTTP 3v72 Crystal Structure of Rat DNA polymerase beta Mutator E295K: Enzyme-dsDNA 3v7j Co-crystal structure of Wild Type Rat polymerase beta: Enzyme-DNA binary complex 3v7k Co-crystal structure of K72E variant of rat polymerase beta: Enzyme-DNA binary complex 3v7l Apo Structure of Rat DNA polymerase beta K72E variant 4do9 Ternary complex of dna polymerase beta with a dideoxy terminated primer and 2'-deoxyguanosine 5'-beta, gamma-monofluoromethylene triphosphate: stereoselective binding of r-isomer 4doa Ternary complex of dna polymerase beta with a dideoxy terminated primer and 2'-deoxyguanosine 5'-beta, gamma-monofluoromethylene triphosphate: non-interactive binding of s-isomer 4dob Ternary complex of DNA polymerase beta with a dideoxy terminated primer and 2'-deoxyguanosine 5'-beta, gamma-monochlororomethylene triphosphate: Stereoselective binding of R-isomer 4doc Ternary complex of dna polymerase beta with a dideoxy terminated primer and 2'-deoxyguanosine 5'-beta, gamma-monochlororomethylene triphosphate:binding of S-isomer 4f5n Open ternary complex of R283K DNA polymerase beta with a metal free dCTP analog 4f5o Open ternary complex of R283K DNA polymerase beta with a one metal bound dCTP analog 4f5p Open ternary mismatch complex of R283K DNA polymerase beta with a dATP analog 4f5q Closed ternary complex of R283K DNA polymerase beta 4f5r Open and closed ternary complex of R283K DNA polymerase beta with a dCTP analog in the same asymmetric unit 4fo6 Crystal structure of the pre-catalytic ternary complex of polymerase lambda with a dATP analog opposite a templating T and an rCMP at the primer terminus. 4gxi R283K DNA polymerase beta binary complex with a templating 8OG 4gxj R283K DNA polymerase beta ternary complex with a templating 8OG and incoming dCTP analog 4gxk R283K DNA polymerase beta ternary complex with a templating 8OG and incoming dATP analog 4i27 Ternary complex of mouse TdT with ssDNA and incoming nucleotide 4i28 Binary complex of mouse TdT with ssDNA and Zn++ 4i29 Binary complex of mouse TdT with ssDNA and Mn++ 4i2a Binary complex of mouse TdT with ssDNA in absence of divalent transition metal ion 4i2b Ternary complex of mouse TdT with ssDNA and AMPcPP 4i2c Ternary complex of mouse TdT with ssDNA and AMPcPP 4i2d Binary complex of mouse TdT with AMPcPP 4i2e Ternary complex of mouse TdT with ssDNA and AMPcPP 4i2f Binary complex of mouse TdT with ssDNA 4i2g Binary complex of mouse TdT with ssDNA 4i2h Ternary complex of mouse TdT with ssDNA and AMPcPP 4i2i Binary complex of mouse TdT with AP5A 4i2j Binary complex of mouse TdT with dCTP 4iqt Tdt core in complex with inhibitor 6-[4-(3-fluorobenzoyl)-1H-pyrrol-2-yl]-2-hydroxy-4-oxohexa-2,5-dienoic acid 4iqu Tdt core in complex with inhibitor (2Z,5E)-6-[4-(4-fluorobenzoyl)-1H-pyrrol-2-yl]-2-hydroxy-4-oxohexa-2,5-dienoic acid 4iqv Tdt core in complex with inhibitor 6-[4-(3-fluorobenzoyl)-1H-pyrrol-2-yl]-2-hydroxy-4-oxohexa-2,5-dienoic acid and ssDNA 4iqw Tdt core in complex with inhibitor (2Z,5E)-6-[4-(4-fluorobenzoyl)-1H-pyrrol-2-yl]-2-hydroxy-4-oxohexa-2,5-dienoic acid and ssDNA 4jwm Ternary complex of D256E mutant of DNA Polymerase Beta 4jwn Ternary complex of D256A mutant of DNA Polymerase Beta 4k4g 4K4G 4k4h 4K4H 4k4i 4K4I 4kld DNA polymerase beta matched substrate complex with Ca2+, 0 s 4kle DNA polymerase beta matched reactant complex with Mg2+, 10 s 4klf DNA polymerase beta matched reactant complex with Mg2+, 20 s 4klg DNA polymerase beta matched product complex with Mg2+, 40 s 4klh DNA polymerase beta matched product complex with Mn2+, 40 s 4kli DNA polymerase beta matched product complex with Mg2+, 90 s 4klj DNA polymerase beta matched product complex with Mg2+, 5 min 4kll DNA polymerase beta matched product complex with Mg2+, 45 min 4klm DNA polymerase beta matched product complex with Mg2+, 11 h 4klo DNA polymerase beta matched nick complex with Mg2+ and PPi, 30 min 4klq Observing a DNA polymerase choose right from wrong. 4kls DNA polymerase beta mismatched reactant complex with Mn2+, 10 min 4klt DNA polymerase beta mismatched product complex with Mn2+, 30 min 4klu DNA polymerase beta mismatched product complex with Mn2+, 15 h 4lvs DNA polymerase beta mismatched substrate complex with Mn2+, 2.5 min 4lzd Human DNA polymerase mu- Apoenzyme 4lzg Binary complex of human DNA Polymerase Mu with DNA 4m04 Human DNA Polymerase Mu ternary complex 4m0a Human DNA Polymerase Mu post-catalytic complex 4m2y Structure of human DNA polymerase beta complexed with 8-BrG as the template base in a 1-nucleotide gapped DNA 4m47 structure of human DNA polymerase complexed with 8-BrG in the template base paired with incoming non-hydrolyzable GTP 4m9g DNA Polymerase Beta E295K Binary Complex 4m9h DNA Polymerase Beta E295K Soaked with dTTP 4m9j DNA Polymerase Beta E295K Soaked with dUMPNPP 4m9l DNA Polymerase Beta E295K Soaked with dCTP 4m9n DNA Polymerase Beta E295K Soaked with dATP 4mf2 Structure of human DNA polymerase beta complexed with O6MG as the template base in a 1-nucleotide gapped DNA 4mf8 4MF8 4mfa 4MFA 4mfc Structure of human DNA polymerase beta complexed with O6MG in the template base paired with incoming non-hydrolyzable CTP 4mff Structure of human DNA polymerase beta complexed with O6MG in the template base paired with incoming non-hydrolyzable TTP 4nlk Structure of human DNA polymerase beta complexed with 8BrG in the template base-paired with incoming non-hydrolyzable CTP 4nln Structure of human DNA polymerase beta complexed with nicked DNA containing a template 8BrG and incoming CTP 4nlz Structure of human DNA polymerase beta complexed with nicked DNA containing a mismatched template 8BrG and incoming GTP 4nm1 Structure of human DNA polymerase beta complexed with a nicked DNA containing a 8BrG-C at N-1 position and G-C at N position 4nm2 Structure of human DNA polymerase beta complexed with a nicked DNA containing a 8BrG-G at N-1 position and G-C at N position 4nxz DNA polymerase beta with O6mG in the template base opposite to incoming non-hydrolyzable TTP with manganese in the active site 4ny8 DNA polymerase beta with O6mG in the template base opposite to incoming non-hydrolyzable CTP with manganese in the active site 4o5c 4O5C 4o5e 4O5E 4o5k 4O5K 4o9m Human DNA polymerase beta complexed with adenylated tetrahydrofuran (abasic site) containing DNA 4p2h 4P2H 4p4m 4P4M 4p4o 4P4O 4p4p 4P4P 4pgq 4PGQ 4pgx 4PGX 4pgy 4PGY 4ph5 4PH5 4pha 4PHA 4phd 4PHD 4phe 4PHE 4php 4PHP 4ppx DNA Polymerase Beta E295K with Spiroiminodihydantoin in Templating Position 4qz8 4QZ8 4qz9 4QZ9 4qza 4QZA 4qzb 4QZB 4qzc 4QZC 4qzd 4QZD 4qze 4QZE 4qzf 4QZF 4qzg 4QZG 4qzh 4QZH 4qzi 4QZI 4r63 4R63 4r64 4R64 4r65 4R65 4r66 4R66 4rpx 4RPX 4rpy 4RPY 4rpz 4RPZ 4rq0 4RQ0 4rq1 4RQ1 4rq2 4RQ2 4rq3 4RQ3 4rq4 4RQ4 4rq5 4RQ5 4rq6 4RQ6 4rq7 4RQ7 4rq8 4RQ8 4rt2 4RT2 4rt3 4RT3 4tup 4TUP 4tuq 4TUQ 4tur 4TUR 4tus 4TUS 4uaw 4UAW 4uay 4UAY 4uaz 4UAZ 4ub1 4UB1 4ub2 4UB2 4ub3 4UB3 4ub4 4UB4 4ub5 4UB5 4ubb 4UBB 4ubc 4UBC 4x5v 4X5V 4xa5 4XA5 4xq8 4XQ8 4xrh 4XRH 4xus 4XUS 4ycx 4YCX 4yd1 4YD1 4yd2 4YD2 4ymm 4YMM 4ymn 4YMN 4ymo 4YMO 4yn4 4YN4 4z6c 4Z6C 4z6d 4Z6D 4z6e 4Z6E 4z6f 4Z6F 5bol 5BOL 5bom 5BOM 5bpc 5BPC 5ca7 5CA7 5cb1 5CB1 5chg 5CHG 5cj7 5CJ7 5cp2 5CP2 5cr0 5CR0 5cwr 5CWR 5d46 5D46 5d49 5D49 5d4b 5D4B 5db6 5DB6 5db7 5DB7 5db8 5DB8 5db9 5DB9 5dba 5DBA 5dbb 5DBB 5dbc 5DBC 5ddm 5DDM 5ddy 5DDY 5dkw 5DKW 5eoz 5EOZ 5iii 5III 5iij 5IIJ 5iik 5IIK 5iil 5IIL 5iim 5IIM 5iin 5IIN 5iio 5IIO 5j0o 5J0O 5j0p 5J0P 5j0q 5J0Q 5j0r 5J0R 5j0s 5J0S 5j0t 5J0T 5j0u 5J0U 5j0v 5J0V 5j0w 5J0W 5j0x 5J0X 5j0y 5J0Y 5j29 5J29 5j2a 5J2A 5j2b 5J2B 5j2c 5J2C 5j2d 5J2D 5j2e 5J2E 5j2f 5J2F 5j2g 5J2G 5j2h 5J2H 5j2i 5J2I 5j2j 5J2J 5j2k 5J2K 7ice DNA POLYMERASE BETA (E.C.2.7.7.7)/DNA COMPLEX, SOAKED IN THE PRESENCE OF CACL2 7icf DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SIX BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF CDCL2 (0.1 MILLIMOLAR) (FOUR-DAY SOAK) 7icg DNA POLYMERASE BETA (E.C.2.7.7.7)/DNA COMPLEX, SOAKED IN THE PRESENCE OF CDCL2 7ich DNA POLYMERASE BETA (E.C.2.7.7.7)/DNA COMPLEX, SOAKED IN THE PRESENCE OF COCL2 7ici DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SIX BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF CRCL3 (0.1 MILLIMOLAR) 7icj DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SIX BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF CUCL2 (0.1 MILLIMOLAR) 7ick DNA POLYMERASE BETA (E.C.2.7.7.7)/DNA COMPLEX, SOAKED IN THE PRESENCE OF MGCL2 7icl DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SIX BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF MNCL2 (0.1 MILLIMOLAR) 7icm DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SIX BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF MNCL2 (1.0 MILLIMOLAR) 7icn DNA POLYMERASE BETA (E.C.2.7.7.7)/DNA COMPLEX, SOAKED IN THE PRESENCE OF NICL2 7ico DNA POLYMERASE BETA (E.C.2.7.7.7)/DNA COMPLEX, SOAKED IN THE PRESENCE OF ZNCL2 7icp DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SIX BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF ZNCL2 (0.01 MILLIMOLAR) 7icq DNA POLYMERASE BETA (E.C.2.7.7.7)/DNA COMPLEX, SOAKED IN THE PRESENCE OF ZNCL2 7icr DNA POLYMERASE BETA (E.C.2.7.7.7)/DNA COMPLEX, SOAKED IN THE PRESENCE OF ZNCL2 7ics DNA POLYMERASE BETA (E.C.2.7.7.7)/DNA COMPLEX, SOAKED IN THE PRESENCE OF ZNCL2 7ict DNA POLYMERASE BETA (E.C.2.7.7.7)/DNA COMPLEX, SOAKED IN THE PRESENCE OF ZNCL2 AND MGCL2 7icu DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SIX BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF CDCL2 (0.1 MILLIMOLAR) 7icv DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SIX BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF MNCL2 (0.1 MILLIMOLAR) AND IN THE ABSENCE OF NACL 8ica DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF DATP (1 MILLIMOLAR) AND CACL2 (5 MILLIMOLAR) 8icb DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF ARTIFICIAL MOTHER LIQUOR 8icc DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA (NO 5'-PHOSPHATE) 8ice DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF DATP (1 MILLIMOLAR) AND CDCL2 (1 MILLIMOLAR) 8icf DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF DATP (10 MILLIMOLAR) AND MGCL2 (50 MILLIMOLAR) 8icg DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF DATP (1 MILLIMOLAR) AND MGCL2 (5 MILLIMOLAR) 8ich DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF DCTP (1 MILLIMOLAR) AND MGCL2 (5 MILLIMOLAR) 8ici DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF DGTP (1 MILLIMOLAR) AND MGCL2 (5 MILLIMOLAR) 8icj DNA POLYMERASE BETA (E.C.2.7.7.7)/DNA COMPLEX + THYMIDINE-5'-TRIPHOSPHATE, SOAKED IN THE PRESENCE OF DTTP AND MGCL2 8ick DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF DATP (1 MILLIMOLAR), MGCL2 (5 MILLIMOLAR), AND MNCL2 (5 MILLIMOLAR) 8icl DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF DATP (1 MILLIMOLAR) AND NICL2 (5 MILLIMOLAR) 8icm DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF DATP (1 MILLIMOLAR), MNCL2 (5 MILLIMOLAR), AND AMMONIUM SULFATE (75 MILLIMOLAR) 8icn DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF ATP (1 MILLIMOLAR) AND MNCL2 (5 MILLIMOLAR) 8ico DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF AZT-TP (1 MILLIMOLAR) AND MNCL2 (5 MILLIMOLAR) 8icp DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF DATP (1 MILLIMOLAR) AND MNCL2 (5 MILLIMOLAR) 8icq DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF OF DATP (0.1 MILLIMOLAR) AND MNCL2 (0.5 MILLIMOLAR) 8icr DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF DATP (1 MILLIMOLAR) AND MNCL2 (5 MILLIMOLAR) 8ics DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF DCTP (1 MILLIMOLAR) AND MNCL2 (5 MILLIMOLAR) 8ict DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF DCTP (1 MILLIMOLAR) AND MNCL2 (5 MILLIMOLAR) 8icu DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF DDATP (1 MILLIMOLAR) AND MNCL2 (5 MILLIMOLAR) 8icv DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF DGTP (1 MILLIMOLAR) AND MNCL2 (5 MILLIMOLAR) 8icw DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF DTTP (1 MILLIMOLAR) AND MNCL2 (5 MILLIMOLAR) 8icx DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF DTTP (1 MILLIMOLAR) AND MNCL2 (5 MILLIMOLAR) 8icy DNA POLYMERASE BETA (E.C.2.7.7.7)/DNA COMPLEX + THYMIDINE-5'-TRIPHOSPHATE, SOAKED IN THE PRESENCE OF DTTP AND MNCL2 8icz DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF OF DATP (1 MILLIMOLAR), MNCL2 (5 MILLIMOLAR), AND LITHIUM SULFATE (75 MILLIMOLAR) 9ica DNA POLYMERASE BETA (E.C.2.7.7.7)/DNA COMPLEX + 2'-DEOXYADENOSINE-5'-O-(1-THIOTRIPHOSPHATE), SOAKED IN THE PRESENCE OF DATP(ALPHA)S AND MNCL2 9icb DNA POLYMERASE BETA (E.C.2.7.7.7)/DNA COMPLEX + 2'-DEOXYADENOSINE-5'-TRIPHOSPHATE, SOAKED IN THE PRESENCE OF DATP AND COCL2 9icc DNA POLYMERASE BETA (E.C.2.7.7.7)/DNA COMPLEX + 2'-DEOXYADENOSINE-5'-TRIPHOSPHATE, SOAKED IN THE PRESENCE OF DATP AND CRCL3 9ice DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF DATP (1 MILLIMOLAR) AND CUCL2 (0.1 MILLIMOLAR) 9icf DNA POLYMERASE BETA (E.C.2.7.7.7)/DNA COMPLEX + 2'-DEOXYADENOSINE-5'-TRIPHOSPHATE, SOAKED IN THE PRESENCE OF DATP AND ZNCL2 9icg DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF DCTP (1 MILLIMOLAR) AND ZNCL2 (1 MILLIMOLAR) 9ich DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF DGTP (1 MILLIMOLAR) AND ZNCL2 (1 MILLIMOLAR) 9ici DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF DTTP (1 MILLIMOLAR) AND ZNCL2 (1 MILLIMOLAR) 9icj DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA 9ick DNA POLYMERASE BETA (E.C.2.7.7.7)/DNA COMPLEX, SOAKED IN THE PRESENCE OF ARTIFICIAL MOTHER LIQUOR 9icl DNA POLYMERASE BETA (E.C.2.7.7.7)/DNA COMPLEX, SOAKED IN THE PRESENCE OF PYROPHOSPHATE AND MNCL2 9icm DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SIX BASE PAIRS OF DOUBLE STRANDED DNA (NO 5'-PHOSPHATE) 9icn DNA POLYMERASE BETA (E.C.2.7.7.7)/DNA COMPLEX + 2',3'-DIDEOXYCYTIDINE-5'-TRIPHOSPHATE, SOAKED IN THE PRESENCE OF DDCTP AND MGCL2 9ico DNA POLYMERASE BETA (E.C.2.7.7.7)/DNA COMPLEX, SOAKED IN THE PRESENCE OF DTTP AND MGCL2 9icp DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SIX BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF PYROPHOSPHATE (1 MILLIMOLAR) AND MGCL2 (5 MILLIMOLAR) 9icq DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SIX BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF DATP (1 MILLIMOLAR) AND MNCL2 (5 MILLIMOLAR) 9icr DNA POLYMERASE BETA (E.C.2.7.7.7)/DNA COMPLEX + 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, SOAKED IN THE PRESENCE OF DCTP AND MNCL2 9ics DNA POLYMERASE BETA (E.C.2.7.7.7)/DNA COMPLEX + 2',3'-DIDEOXYCYTIDINE-5'-TRIPHOSPHATE, SOAKED IN THE PRESENCE OF DDCTP AND MNCL2 9ict DNA POLYMERASE BETA (E.C.2.7.7.7)/DNA COMPLEX + 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, SOAKED IN THE PRESENCE OF DGTP AND MNCL2 9icu DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SIX BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF DTTP (1 MILLIMOLAR) AND MNCL2 (5 MILLIMOLAR) 9icv DNA POLYMERASE BETA (E.C.2.7.7.7)/DNA COMPLEX + 2'-DEOXYADENOSINE-5'-TRIPHOSPHATE, SOAKED IN THE PRESENCE OF DATP AND ZNCL2 9icw DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SIX BASE PAIRS OF DNA; NATIVE STRUCTURE 9icx DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SIX BASE PAIRS OF DNA (NON GAPPED DNA ONLY) 9icy DNA POLYMERASE BETA (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA (NON GAPPED DNA ONLY) - Links (links to other resources describing this domain)
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PFAM DNA_polymeraseX INTERPRO IPR002054 PROSITE DNA_POLYMERASE_X