| SMART accession number: | SM00951
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| Description: |
QLQ is named after the conserved Gln, Leu, Gln motif. QLQ is found at the N-terminus of SWI2/SNF2 protein, which has been shown to be involved in protein-protein interactions. QLQ has been postulated to be involved in mediating protein interactions (PUBMED:12974814). |
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| Interpro abstract (IPR014978): |
QLQ is named after the conserved Gln, Leu, Gln motif. QLQ is found at the N terminus of SWI2/SNF2 protein, which has been shown to be involved in protein-protein interactions. QLQ has been postulated to be involved in mediating protein interactions [(PUBMED:12974814)].
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| GO process: | regulation of transcription, DNA-dependent (GO:0006355) |
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| GO component: | nucleus (GO:0005634) |
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| GO function: | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides (GO:0016818), ATP binding (GO:0005524) |
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| Family alignment: |
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Click on the following links for more information.
- Evolution (species in which this domain is found)
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- Cellular role (predicted cellular role)
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Cellular role: interaction
- Literature (relevant references for this domain)
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Primary literature is listed below; Automatically-derived, secondary literature is also avaliable.
- Kim JH, Choi D, Kende H
- The AtGRF family of putative transcription factors is involved in leaf andcotyledon growth in Arabidopsis.
- Plant J. 2003; 36: 94-104
- Display abstract
Previously, we identified a novel rice gene, GROWTH-REGULATING FACTOR1(OsGRF1), which encodes a putative transcription factor that appears toplay a regulatory role in stem elongation. We now describe the GRF genefamily of Arabidopsis thaliana (AtGRF), which comprises nine members. Thededuced AtGRF proteins contain the same characteristic regions--the QLQ(Gln, Leu, Gln) and WRC (Trp, Arg, Cys) domains--as do OsGRF1 and relatedproteins in rice, as well as features indicating a function intranscriptional regulation. Most of the AtGRF genes are strongly expressedin actively growing and developing tissues, such as shoot tips, flowerbuds, and roots, but weakly in mature stem and leaf tissues.Overexpression of AtGRF1 and AtGRF2 resulted in larger leaves andcotyledons, as well as in delayed bolting of the inflorescence stem whencompared to wild-type plants. In contrast, triple insertional null mutantsof AtGRF1-AtGRF3 had smaller leaves and cotyledons, whereas single mutantsdisplayed no changes in phenotype and double mutants displayed only minorones. The alteration of leaf growth in overexpressors and triple mutantswas based on an increase or decrease in cell size, respectively. Theseresults indicate that AtGRF proteins play a role in the regulation of cellexpansion in leaf and cotyledon tissues.
- Links (links to other resources describing this domain)
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