|SMART accession number:||SM00956|
|Description:||This DNA-binding domain is found in the RecQ helicase among others and has a helix-turn-helix structure. The RQC domain, found only in RecQ family enzymes, is a high affinity G4 DNA binding domain (PUBMED:16530788).|
|Interpro abstract (IPR018982):|
This entry represents the RQC domain, which is a DNA-binding domain found only in RecQ family enzymes. RecQ family helicases can unwind G4 DNA, and play important roles at G-rich domains of the genome, including the telomeres, rDNA, and immunoglobulin switch regions. This domain has a helix-turn-helix structure and acts as a high affinity G4 DNA binding domain [(PUBMED:16530788)]. Binding of RecQ to Holliday junctions involves both the RQC and the HRDC domains.
|GO process:||DNA repair (GO:0006281), DNA replication (GO:0006260)|
|GO function:||ATP-dependent 3'-5' DNA helicase activity (GO:0043140)|
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- Evolution (species in which this domain is found)
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- Literature (relevant references for this domain)
- Structure (3D structures containing this domain)
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