SAM_HD_adjacentSAM homeodomain adjacent domain |
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| SMART accession number: | SM01426
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| Description: |
The SAM HD adjacent domain is a conserved motif found immediately downstream of the homeodomain in SAMSARA three amino acid loop extension (TALE) homeodomain proteins (PMID: 30644818). This domain has been identified in SAMSARA proteins from a broad range of brown algae. |
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| Family alignment: |
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There are 0 SAM_HD_adjacent domains in 0 proteins in SMART's nrdb database.
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Literature (relevant references for this domain)
Primary literature is listed below; Automatically-derived, secondary literature is also avaliable.
- Arun A et al.
- Convergent recruitment of TALE homeodomain life cycle regulators to directsporophyte development in land plants and brown algae.
- Elife. 2019; 8: 0-0
- Display abstract
Three amino acid loop extension homeodomain transcription factors (TALE HD TFs)act as life cycle regulators in green algae and land plants. In mosses theseregulators are required for the deployment of the sporophyte developmentalprogram. We demonstrate that mutations in either of two TALE HD TF genes,OUROBOROS or SAMSARA, in the brown alga Ectocarpus result in conversion of thesporophyte generation into a gametophyte. The OUROBOROS and SAMSARA proteinsheterodimerise in a similar manner to TALE HD TF life cycle regulators in thegreen lineage. These observations demonstrate that TALE-HD-TF-based life cycleregulation systems have an extremely ancient origin, and that these systems have been independently recruited to regulate sporophyte developmental programs in at least two different complex multicellular eukaryotic supergroups, Archaeplastida and Chromalveolata.
