• Links (links to other resources describing this domain)

    SAM / Pointed domain
    SMART accession number:SM00251
    Description: A subfamily of the SAM domain
    Interpro abstract (IPR003118):

    The highly conserved PNT (or Pointed) domain is found within a subset of the Ets transcription factors, including mammalian Ets-1, Ets-2, Erg, Fli-1, GABPalpha, and Tel, as well as Drosophila Pnt-P2 and Yan. The PNT domain is structurally related to the larger group of SAM domains through a common tertiary arrangement of four alpha-helices. A role in protein-protein association has been established for the PNT domain [(PUBMED:10828014), (PUBMED:15351649)].

    GO component:nucleus (GO:0005634)
    GO function:sequence-specific DNA binding (GO:0043565)
    Family alignment:
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    There are 1628 SAM_PNT domains in 1626 proteins in SMART's nrdb database.

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