GEDDynamin GTPase effector domain
|SMART accession number:||SM00302|
|Interpro abstract (IPR003130):|
Dynamin GTPase effector domain found in proteins related to dynamin.
Dynamin is a GTP-hydrolysing protein that is an essential participant in clathrin-mediated endocytosis by cells. It self-assembles into 'collars' in vivo at the necks of invaginated coated pits; the self-assembly of dynamin being coordinated by the GTPase domain. Mutation studies indicate that dynamin functions as a molecular regulator of receptor-mediated endocytosis [(PUBMED:10206643)].
|GO function:||GTP binding (GO:0005525), GTPase activity (GO:0003924)|
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