SNc

Staphylococcal nuclease homologues
SNc
SMART accession number:SM00318
Description:
Interpro abstract (IPR006021):

Staphylococcus aureus nuclease (SNase) homologues, previously thought to be restricted to bacteria and archaea, are also in eukaryotes. Staphylococcal nuclease has multidomain organisation [(PUBMED:9003410)]. The human cellular coactivator p100 contains four repeats, each of which is a SNase homologue. These repeats are unlikely to possess SNase-like activities as each lacks equivalent SNase catalytic residues, yet they may mediate p100's single-stranded DNA-binding function [(PUBMED:9041650)]. alA variety of proteins including many that are still uncharacterised belong to this group.

GO function:hydrolase activity, acting on ester bonds (GO:0016788), nucleic acid binding (GO:0003676)
Family alignment:
View or

There are 1525 SNc domains in 1041 proteins in SMART's nrdb database.

Click on the following links for more information.