Staphylococcal nuclease homologues
SMART accession number:SM00318
Interpro abstract (IPR006021):

Staphylococcus aureus nuclease (SNase) homologues, previously thought to be restricted to bacteria and archaea, are also in eukaryotes. Staphylococcal nuclease has multidomain organisation [(PUBMED:9003410)]. The human cellular coactivator p100 contains four repeats, each of which is a SNase homologue. These repeats are unlikely to possess SNase-like activities as each lacks equivalent SNase catalytic residues, yet they may mediate p100's single-stranded DNA-binding function [(PUBMED:9041650)]. alA variety of proteins including many that are still uncharacterised belong to this group.

GO function:hydrolase activity, acting on ester bonds (GO:0016788), nucleic acid binding (GO:0003676)
Family alignment:
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There are 1525 SNc domains in 1041 proteins in SMART's nrdb database.

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