Spc7Spc7 kinetochore protein
|SMART accession number:||SM00787|
|Description:||This domain is found in cell division proteins which are required for kinetochore-spindle association.|
|Interpro abstract (IPR013253):|
This domain is found in cell division proteins which are required for kinetochore-spindle association [(PUBMED:15371542)]. Proteins contain this domain include budding yeast Spc105 and fission yeast Spc7.
Spc7 is a component of the NMS (Ndc80-MIND-Spc7) super complex, which has a role in kinetochore function during late meiotic prophase and throughout the mitotic cell cycle [(PUBMED:22711988)]. Spc105 and Kre28 forms a kinetochore complex, which is required for kinetochore binding by a discrete subset of kMAPs (BIM1, BIK1 and SLK19) and motors (CIN8, KAR3) [(PUBMED:19893618)].
Click on the following links for more information.
- Evolution (species in which this domain is found)
- Literature (relevant references for this domain)
- Links (links to other resources describing this domain)