Spc7

Spc7 kinetochore protein
Spc7
SMART accession number:SM00787
Description: This domain is found in cell division proteins which are required for kinetochore-spindle association.
Interpro abstract (IPR013253):

This domain is found in cell division proteins which are required for kinetochore-spindle association [(PUBMED:15371542)]. Proteins contain this domain include budding yeast Spc105 and fission yeast Spc7.

Spc7 is a component of the NMS (Ndc80-MIND-Spc7) super complex, which has a role in kinetochore function during late meiotic prophase and throughout the mitotic cell cycle [(PUBMED:22711988)]. Spc105 and Kre28 forms a kinetochore complex, which is required for kinetochore binding by a discrete subset of kMAPs (BIM1, BIK1 and SLK19) and motors (CIN8, KAR3) [(PUBMED:19893618)].

Family alignment:
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There are 92 Spc7 domains in 92 proteins in SMART's nrdb database.

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