THNThaumatin family |
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| SMART accession number: | SM00205 |
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| Description: | The thaumatin family gathers proteins related to plant pathogenesis. The thaumatin family includes very basic members with extracellular and vacuolar localization. Thaumatin itsel is a potent sweet-tasting protein. Several members of this family display significant in vitro activity of inhibiting hyphal growth or spore germination of various fungi probably by a membrane permeabilizing mechanism. |
| Interpro abstract (IPR001938): | Pathogenesis related (PR) proteins, which are induced by various agents ranging from ethylene to pathogens, are structurally diverse and apparently ubiquitous in plants (PUBMED:1463856): they include thaumatin, osmotin, tobacco major and minor PR proteins, alpha-amylase/trypsin inhibitor, and P21 and PWIR2 soybean and wheat leaf proteins. The proteins are involved in systematically acquired resistance and stress response in plants, although their precise role is unknown (PUBMED:1463856). Thaumatin is an intensely sweet tasting protein (about 100,000 times sweeter than sucrose (PUBMED:7049841)) found in the West African shrub Thaumatococcus daniellii: it is induced by attack by viroids, which are single-stranded unencapsulated RNA molecules that do not code for protein. Like other PR proteins, thaumatin is predicted to have a mainly beta structure, with a high content of beta-turns and little helix (PUBMED:1463856). Tobacco cells exposed to gradually increased salt concentrations develop a greatly increased tolerance to salt, due to the expression of osmotin a member of the PR protein family. Wheat plants attacked by barley powdery mildew express a PR protein (PWIR2), which results in resistance against that infection (PUBMED:1650615). The similarity between this and other PR proteins to the maize alpha-amylase/trypsin inhibitor has suggested that PR proteins may act as some form of inhibitor (PUBMED:1650615). |
| Family alignment: |
There are 281 THN domains in 280 proteins in SMART's nrdb database.
Click on the following links for more information.
- Evolution (species in which this domain is found)
- Structure (3D structures containing this domain)
- Links (links to other resources describing this domain)
to expand nodes. To display all proteins with a THN domain in a specific node, click on it.
