PDB code | Main view | Title | 1aj6 |  | NOVOBIOCIN-RESISTANT MUTANT (R136H) OF THE N-TERMINAL 24 KDA FRAGMENT OF DNA GYRASE B COMPLEXED WITH NOVOBIOCIN AT 2.3 ANGSTROMS RESOLUTION |
1bgw |  | TOPOISOMERASE RESIDUES 410-1202, |
1bjt |  | TOPOISOMERASE II RESIDUES 409-1201 |
1ei1 |  | DIMERIZATION OF E. COLI DNA GYRASE B PROVIDES A STRUCTURAL MECHANISM FOR ACTIVATING THE ATPASE CATALYTIC CENTER |
1kij |  | Crystal structure of the 43K ATPase domain of Thermus thermophilus gyrase B in complex with novobiocin |
1kzn |  | Crystal Structure of E. coli 24kDa Domain in Complex with Clorobiocin |
1pvg |  | Crystal Structure of the ATPase region of Saccharomyces Cerevisiae topoisomerase II |
1qzr |  | CRYSTAL STRUCTURE OF THE ATPASE REGION OF SACCHAROMYCES CEREVISIAE TOPOISOMERASE II BOUND TO ICRF-187 (DEXRAZOXANE) |
1s14 |  | Crystal structure of Escherichia coli Topoisomerase IV ParE 24kDa subunit |
1s16 |  | Crystal Structure of E. coli Topoisomerase IV ParE 43kDa subunit complexed with ADPNP |
1zxm |  | Human Topo IIa ATPase/AMP-PNP |
1zxn |  | Human DNA topoisomerase IIa ATPase/ADP |
2rgr |  | Topoisomerase IIA bound to G-segment DNA |
2xco |  | The 3.1A crystal structure of the catalytic core (B'A' region) of Staphylococcus aureus DNA Gyrase |
2xcq |  | The 2.98A crystal structure of the catalytic core (B'A' region) of Staphylococcus aureus DNA Gyrase |
2xcr |  | The 3.5A crystal structure of the catalytic core (B'A' region) of Staphylococcus aureus DNA Gyrase complexed with GSK299423 and DNA |
2xcs |  | The 2.1A crystal structure of S. aureus Gyrase complex with GSK299423 and DNA |
2xct |  | The twinned 3.35A structure of S. aureus Gyrase complex with Ciprofloxacin and DNA |
2xkj |  | CRYSTAL STRUCTURE OF CATALYTIC CORE OF A. BAUMANNII TOPO IV (PARE- PARC FUSION TRUNCATE) |
2xkk |  | CRYSTAL STRUCTURE OF MOXIFLOXACIN, DNA, and A. BAUMANNII TOPO IV ( PARE-PARC FUSION TRUNCATE) |
2zjt |  | Crystal structure of dna gyrase B' domain sheds lights on the mechanism for T-segment navigation |
3cwv |  | Crystal structure of B-subunit of the DNA gyrase from Myxococcus xanthus |
3foe |  | Structural insight into the quinolone-DNA cleavage complex of type IIA topoisomerases |
3fof |  | Structural insight into the quinolone-DNA cleavage complex of type IIA topoisomerases |
3fv5 |  | Crystal Structure of E. coli Topoisomerase IV co-complexed with inhibitor |
3g75 |  | Crystal structure of Staphylococcus aureus Gyrase B co-complexed with 4-METHYL-5-[3-(METHYLSULFANYL)-1H-PYRAZOL-5-YL]-2-THIOPHEN-2-YL-1,3-THIAZOLE inhibitor |
3g7b |  | Staphylococcus aureus Gyrase B co-complex with METHYL ({5-[4-(4-HYDROXYPIPERIDIN-1-YL)-2-PHENYL-1,3-THIAZOL-5-YL]-1H-PYRAZOL-3-YL}METHYL)CARBAMATE inhibitor |
3g7e |  | Crystal structure of E. coli Gyrase B co-complexed with PROP-2-YN-1-YL {[5-(4-PIPERIDIN-1-YL-2-PYRIDIN-3-YL-1,3-THIAZOL-5-YL)-1H-PYRAZOL-3-YL]METHYL}CARBAMATE inhibitor |
3ig0 |  | crystal structure of the second part of the Mycobacterium tuberculosis DNA gyrase reaction core: the TOPRIM domain at 2.1 A resolution |
3k9f |  | Detailed structural insight into the quinolone-DNA cleavage complex of type IIA topoisomerases |
3ksa |  | Detailed structural insight into the DNA cleavage complex of type IIA topoisomerases (cleaved form) |
3ksb |  | Detailed structural insight into the DNA cleavage complex of type IIA topoisomerases (re-sealed form) |
3l4j |  | Topoisomerase II-DNA cleavage complex, apo |
3l4k |  | Topoisomerase II-DNA cleavage complex, metal-bound |
3lnu |  | Crystal structure of ParE subunit |
3lps |  | Crystal structure of parE |
3ltn |  | Inhibitor-stabilized topoisomerase IV-DNA cleavage complex (S. pneumoniae) |
3m4i |  | Crystal structure of the second part of the Mycobacterium tuberculosis DNA gyrase reaction core: the TOPRIM domain at 1.95 A resolution |
3nuh |  | A domain insertion in E. coli GyrB adopts a novel fold that plays a critical role in gyrase function |
3qx3 |  | Human topoisomerase IIbeta in complex with DNA and etoposide |
3rad |  | Quinolone(Clinafloxacin)-DNA cleavage complex of type IV topoisomerase from S. pneumoniae |
3rae |  | Quinolone(Levofloxacin)-DNA cleavage complex of type IV topoisomerase from S. pneumoniae |
3raf |  | Quinazolinedione-DNA cleavage complex of type IV topoisomerase from S. pneumoniae |
3ttz |  | Crystal structure of a topoisomerase ATPase inhibitor |
3u2d |  | S. aureus GyrB ATPase domain in complex with small molecule inhibitor |
3u2k |  | S. aureus GyrB ATPase domain in complex with a small molecule inhibitor |
3zkb |  | CRYSTAL STRUCTURE OF THE ATPASE REGION OF Mycobacterium tuberculosis GyrB WITH AMPPNP |
3zkd |  | CRYSTAL STRUCTURE OF THE ATPASE REGION OF Mycobacterium tuberculosis GyrB WITH AMPPNP |
3zm7 |  | CRYSTAL STRUCTURE OF THE ATPASE REGION OF Mycobacterium tuberculosis GyrB WITH AMPPCP |
4b6c |  | Structure of the M. smegmatis GyrB ATPase domain in complex with an aminopyrazinamide |
4bae |  | Optimisation of pyrroleamides as mycobacterial GyrB ATPase inhibitors: Structure Activity Relationship and in vivo efficacy in the mouse model of tuberculosis |
4bul |  | Novel hydroxyl tricyclics (e.g. GSK966587) as potent inhibitors of bacterial type IIA topoisomerases |
4duh |  | Crystal structure of 24 kDa domain of E. coli DNA gyrase B in complex with small molecule inhibitor |
4em7 |  | Crystal structure of a topoisomerase ATP inhibitor |
4emv |  | Crystal structure of a topoisomerase ATP inhibitor |
4fm9 |  | Human topoisomerase II alpha bound to DNA |
4g0u |  | Human topoisomerase IIbeta in complex with DNA and amsacrine |
4g0v |  | Human topoisomerase iibeta in complex with DNA and mitoxantrone |
4g0w |  | Human topoisomerase iibeta in complex with DNA and ametantrone |
4gee |  | Pyrrolopyrimidine inhibitors of DNA gyrase B and topoisomerase IV, part I: structure guided discovery and optimization of dual targeting agents with potent, broad-spectrum enzymatic activity. |
4gfh |  | Topoisomerase II-DNA-AMPPNP complex |
4gfn |  | Pyrrolopyrimidine inhibitors of dna gyrase b and topoisomerase iv, part i: structure guided discovery and optimization of dual targeting agents with potent, broad-spectrum enzymatic |
4ggl |  | Pyrrolopyrimidine inhibitors of dna gyrase b and topoisomerase iv, part i: structure guided discovery and optimization of dual targeting agents with potent, broad-spectrum enzymatic activity |
4hxw |  | Pyrrolopyrimidine inhibitors of dna gyrase b and topoisomerase iv, part i: structure guided discovery and optimization of dual targeting agents with potent, broad-spectrum enzymatic activity. |
4hxz |  | Pyrrolopyrimidine inhibitors of dna gyrase b and topoisomerase iv, part i: structure guided discovery and optimization of dual targeting agents with potent, broad-spectrum enzymatic activity. |
4hy1 |  | Pyrrolopyrimidine inhibitors of dna gyrase b and topoisomerase iv, part i: structure guided discovery and optimization of dual targeting agents with potent, broad-spectrum enzymatic activity. |
4hym |  | Pyrrolopyrimidine inhibitors of dna gyrase b and topoisomerase iv, part i: structure guided discovery and optimization of dual targeting agents with potent, broad-spectrum enzymatic activity. |
4hyp |  | Pyrrolopyrimidine inhibitors of dna gyrase b and topoisomerase iv, part i: structure guided discovery and optimization of dual targeting agents with potent, broad-spectrum enzymatic activity. |
4hz0 |  | Pyrrolopyrimidine inhibitors of dna gyrase b and topoisomerase iv, part i: structure guided discovery and optimization of dual targeting agents with potent, broad-spectrum enzymatic activity. |
4hz5 |  | Pyrrolopyrimidine inhibitors of dna gyrase b and topoisomerase iv, part i: structure guided discovery and optimization of dual targeting agents with potent, broad-spectrum enzymatic activity |
4i3h |  | A three-gate structure of topoisomerase IV from Streptococcus pneumoniae |
4j3n |  | Human Topoisomerase Iibeta in complex with DNA |
4juo |  | A low-resolution three-gate structure of topoisomerase IV from Streptococcus pneumoniae in space group H32 |
4k4o |  | The DNA Gyrase B ATP binding domain of Enterococcus faecalis in complex with a small molecule inhibitor |
4kfg |  | The DNA Gyrase B ATP binding domain of Escherichia coli in complex with a small molecule inhibitor. |
4koe |  | 4KOE |
4kpe |  | 4KPE |
4kpf |  | 4KPF |
4kqv |  | Topoisomerase iv atp binding domain of francisella tularensis in complex with a small molecule inhibitor |
4ksg |  | Dna gyrase atp binding domain of enterococcus faecalis in complex with a small molecule inhibitor (4-[(1S,5R,6R)-6-AMINO-1-METHYL-3-AZABICYCLO[3.2.0]HEPT-3-YL]-6-FLUORO-N-METHYL-2-[(2-METHYLPYRIMIDIN-5-YL)OXY]-9H-PYRIMIDO[4,5-B]INDOL-8-AMINE) |
4ksh |  | Dna gyrase atp binding domain of enterococcus faecalis in complex with a small molecule inhibitor (7-({4-[(3R)-3-AMINOPYRROLIDIN-1-YL]-5-CHLORO-6-ETHYL-7H-PYRROLO[2,3-D]PYRIMIDIN-2-YL}SULFANYL)-1,5-NAPHTHYRIDIN-1(4H)-OL) |
4ktn |  | Dna gyrase atp binding domain of enterococcus faecalis in complex with a small molecule inhibitor ((3S)-1-[2-(PYRIDO[2,3-B]PYRAZIN-7-YLSULFANYL)-9H-PYRIMIDO[4,5-B]INDOL-4-YL]PYRROLIDIN-3-AMINE) |
4lp0 |  | Crystal structure of a topoisomerase ATP inhibitor |
4lpb |  | Crystal structure of a topoisomerase ATPase inhibitor |
4mb9 |  | Structure of Streptococcus pneumonia ParE in complex with AZ13102335 |
4mbc |  | Structure of Streptococcus pneumonia ParE in complex with AZ13053807 |
4mot |  | Structure of Streptococcus pneumonia pare in complex with AZ13072886 |
4p8o |  | 4P8O |
4plb |  | 4PLB |
4prv |  | 4PRV |
4prx |  | 4PRX |
4pu9 |  | 4PU9 |
4r1f |  | 4R1F |
4tma |  | 4TMA |
4url |  | 4URL |
4urm |  | 4URM |
4urn |  | 4URN |
4uro |  | 4URO |
4wub |  | 4WUB |
4wuc |  | 4WUC |
4wud |  | 4WUD |
4xtj |  | 4XTJ |
4z2c |  | 4Z2C |
4z2d |  | 4Z2D |
4z2e |  | 4Z2E |
4z3o |  | 4Z3O |
4z4q |  | 4Z4Q |
4z53 |  | 4Z53 |
4zvi |  | 4ZVI |
5boc |  | 5BOC |
5bod |  | 5BOD |
5bs3 |  | 5BS3 |
5bs8 |  | 5BS8 |
5bta |  | 5BTA |
5btc |  | 5BTC |
5btd |  | 5BTD |
5btf |  | 5BTF |
5btg |  | 5BTG |
5bti |  | 5BTI |
5btl |  | 5BTL |
5btn |  | 5BTN |
5cdm |  | 5CDM |
5cdn |  | 5CDN |
5cdo |  | 5CDO |
5cdp |  | 5CDP |
5cdq |  | 5CDQ |
5cdr |  | 5CDR |
5cph |  | 5CPH |
5ctu |  | 5CTU |
5ctw |  | 5CTW |
5ctx |  | 5CTX |
5cty |  | 5CTY |
5d6p |  | 5D6P |
5d6q |  | 5D6Q |
5d7c |  | 5D7C |
5d7d |  | 5D7D |
5d7r |  | 5D7R |
5eix |  | 5EIX |
5iwi |  | 5IWI |
5iwm |  | 5IWM |
5l3j |  | 5L3J |