VIT

Vault protein Inter-alpha-Trypsin domain
VIT
SMART accession number:SM00609
Description:
Interpro abstract (IPR013694):

Inter-alpha-trypsin inhibitors (ITIs) consist of one light chain and a variable set of heavy chains. ITIs play a role in extracellular matrix (ECM) stabilisation and tumour metastasis as well as in plasma protease inhibition [(PUBMED:14744536)]. The vault protein inter-alpha-trypsin (VIT) domain described here is found to the N terminus of a von Willebrand factor type A domain (IPR002035) in ITI heavy chains (ITIHs) and their precursors.

Family alignment:
View or

There are 206 VIT domains in 204 proteins in SMART's nrdb database.

Click on the following links for more information.