metaSMART is dedicated to the exploration of protein domains and domain architectures in various metagenomics datasets. We are in the currenlty processing several additional datasets, which will be available for analysis in the coming months. If you have a suggestion for a publicly available metagenomics dataset which should be included, please contact us.

Architecture analysis

Similar to standard SMART architecture analysis, you can search for proteins with combinations of SMART and Pfam domains, optionally restriciting the search to one or more metagenomics datasets.

Domain selection

Examples: #1, #2

Datasets:

Sargasso Sea
Minnesota farm soil
Acid mine drainage biofilm
"Whale fall" carcasses
Human gut gene catalogue

Compare and explore domain architectures

The domain architecture is defined as the linear order of all SMART domains in the protein sequence. Note that this excludes Pfam domains and intrinsic features.

Explore architectures

Compare architectures

Dataset 1:
Dataset 2:

Display shared architectures Display unique architectures