Letunic et al. (2017) Nucleic Acids Res doi: 10.1093/nar/gkx922
Letunic et al. (2020) Nucleic Acids Res doi: 10.1093/nar/gkaa937

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ChtBD1 Chitin binding domain

SMART accession number:	SM00270
Description:	-
Interpro abstract (IPR001002):	A number of plant and fungal proteins that bind N-acetylglucosamine (e.g. solanaceous lectins of tomato and potato, plant endochitinases, the wound-induced proteins: hevein, win1 and win2, and the Kluyveromyces lactis killer toxin alpha subunit) contain this domain [ (PUBMED:1757999) ]. The domain may occur in one or more copies and is thought to be involved in recognition or binding of chitin subunits [ (PUBMED:2070799) (PUBMED:1375935) ]. In chitinases, as well as in the potato wound-induced proteins, the 43-residue domain directly follows the signal sequence and is therefore at the N terminus of the mature protein; in the killer toxin alpha subunit it is located in the central section of the protein.
GO function:	chitin binding (GO:0008061)
Family alignment:	View or CHROMA formatHMM/Web logoCLUSTALW formatMSF formatFASTA formatPIR format

There are 7172 ChtBD1 domains in 3459 proteins in SMART's nrdb database.

Click on the following links for more information.

• Evolution (species in which this domain is found)

• Taxonomic distribution of proteins containing ChtBD1 domain.

  This tree includes only several representative species. The complete taxonomic breakdown of all proteins with ChtBD1 domain is also avaliable.

  Click on the protein counts, or double click on taxonomic names to display all proteins containing ChtBD1 domain in the selected taxonomic class.

• Metabolism (metabolic pathways involving proteins which contain this domain)

• Click the image to view the interactive version of the map in iPath

  % proteins involved KEGG pathway ID Description 100.00 map00530 Aminosugars metabolism This information is based on mapping of SMART genomic protein database to KEGG orthologous groups. Percentage points are related to the number of proteins with ChtBD1 domain which could be assigned to a KEGG orthologous group, and not all proteins containing ChtBD1 domain. Please note that proteins can be included in multiple pathways, ie. the numbers above will not always add up to 100%.

• Structure (3D structures containing this domain)

• 3D Structures of ChtBD1 domains in PDB

  PDB code	Main view	Title
  1ehd		CRYSTAL STRUCTURE OF URTICA DIOICA AGGLUTININ ISOLECTIN VI
  1ehh		CRYSTAL STRUCTURE OF URTICA DIOICA AGGLUTININ ISOLECTIN VI COMPLEX WITH TRI-N-ACETYLCHITOTRIOSE
  1eis		UDA UNCOMPLEXED FORM. CRYSTAL STRUCTURE OF URTICA DIOICA AGGLUTININ, A SUPERANTIGEN PRESENTED BY MHC MOLECULES OF CLASS I AND CLASS II
  1en2		UDA TETRASACCHARIDE COMPLEX. CRYSTAL STRUCTURE OF URTICA DIOICA AGGLUTININ, A SUPERANTIGEN PRESENTED BY MHC MOLECULES OF CLASS I AND CLASS II
  1enm		UDA TRISACCHARIDE COMPLEX. CRYSTAL STRUCTURE OF URTICA DIOICA AGGLUTININ, A SUPERANTIGEN PRESENTED BY MHC MOLECULES OF CLASS I AND CLASS II
  1hev		HEVEIN: THE NMR ASSIGNMENT AND AN ASSESSMENT OF SOLUTION-STATE FOLDING FOR THE AGGLUTININ-TOXIN MOTIF
  1iqb		Crystal Structure of Urtica dioica Agglutinin Isolectin I
  1k7t		Crystal Structure Analysis of crosslinked-WGA3/GlcNAcbeta1,6Gal complex
  1k7u		Crystal Structure Analysis of crosslinked-WGA3/GlcNAcbeta1,4GlcNAc complex
  1k7v		Crystal Structure Analysis of crosslinked-WGA3/GlcNAcbeta1,6Galbeta1,4Glc
  1mmc		1H NMR STUDY OF THE SOLUTION STRUCTURE OF AC-AMP2
  1p9g		Crystal structure of a novel antifungal protein distinct with five disulfide bridges from Ecommia ulmoides Oliver at atomic resolution
  1p9z		The Solution Structure of Antifungal Peptide Distinct With a Five-disulfide Motif from Eucommia ulmoides Oliver
  1q9b		CRYSTAL STRUCTURE ANALYSIS OF Hev b 6.02 (HEVEIN) AT 1.5 ANGSTROMS RESOLUTION
  1t0w		25 NMR structures of Truncated Hevein of 32 aa (Hevein-32) complex with N,N,N-triacetylglucosamina
  1uha		Crystal Structure of Pokeweed Lectin-D2
  1ulk		Crystal Structure of Pokeweed Lectin-C
  1ulm		Crystal Structure of Pokeweed Lectin-D2 complexed with tri-N-acetylchitotriose
  1uln		Crystal Structure of Pokeweed Lectin-D1
  1wgc		2.2 ANGSTROMS RESOLUTION STRUCTURE ANALYSIS OF TWO REFINED N-ACETYLNEURAMINYLLACTOSE-WHEAT GERM AGGLUTININ ISOLECTIN COMPLEXES
  1wgt		X-RAY STRUCTURE OF WHEAT GERM AGGLUTININ ISOLECTIN 3
  1wkx		Crystal Structure of a Hev b 6.02 Isoallergen
  1znt		18 NMR structures of AcAMP2-Like Peptide with non Natural Fluoroaromatic Residue (AcAMP2F18Pff/Y20Pff) complex with N,N,N-triacetylchitotriose
  1zuv		24 NMR structures of AcAMP2-Like Peptide with Phenylalanine 18 mutated to Tryptophan
  1zwu		30 NMR structures of AcAMP2-like peptide with non natural beta-(2-naphthyl)-alanine residue.
  2cwg		CRYSTALLOGRAPHIC REFINEMENT AND STRUCTURE ANALYSIS OF THE COMPLEX OF WHEAT GERM AGGLUTININ WITH A BIVALENT SIALOGLYCOPEPTIDE FROM GLYCOPHORIN A
  2dkv		Crystal structure of class I chitinase from Oryza sativa L. japonica
  2kus		Spatial structure of Antimicrobial Peptide Sm-AMP-1.1a
  2lb7		Hevein-type Antifungal Peptide with a Unique 10-Cysteine Motif
  2n1s		2N1S
  2uvo		High Resolution Crystal Structure of Wheat Germ Agglutinin in Complex with N-Acetyl-D-Glucosamine
  2wgc		2.2 ANGSTROMS RESOLUTION STRUCTURE ANALYSIS OF TWO REFINED N-ACETYLNEURAMINYLLACTOSE-WHEAT GERM AGGLUTININ ISOLECTIN COMPLEXES
  2x3t		Glutaraldehyde-crosslinked wheat germ agglutinin isolectin 1 crystal soaked with a synthetic glycopeptide
  2x52		CRYSTAL STRUCTURE OF WHEAT GERM AGGLUTININ ISOLECTIN 3 IN COMPLEX WITH A SYNTHETIC DIVALENT CARBOHYDRATE LIGAND
  3iwr		Crystal structure of class I chitinase from Oryza sativa L. japonica
  4aml		CRYSTAL STRUCTURE OF WHEAT GERM AGGLUTININ ISOLECTIN 1 IN COMPLEX WITH GLYCOSYLURETHAN
  4mpi		4MPI
  4wp4		4WP4
  4z8i		4Z8I
  4zxm		4ZXM
  7wga		2.2 ANGSTROMS RESOLUTION STRUCTURE ANALYSIS OF TWO REFINED N-ACETYLNEURAMINYLLACTOSE-WHEAT GERM AGGLUTININ ISOLECTIN COMPLEXES
  9wga		2.2 ANGSTROMS RESOLUTION STRUCTURE ANALYSIS OF TWO REFINED N-ACETYLNEURAMINYLLACTOSE-WHEAT GERM AGGLUTININ ISOLECTIN COMPLEXES

• Links (links to other resources describing this domain)

• INTERPRO	IPR001002
  PFAM	chitin_binding
  PROSITE	CHITIN_BINDING

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