Domain of unknown function (DUF3402)
SMART accession number:SM01293
Description: This domain is functionally uncharacterised. This domain is found in eukaryotes. This presumed domain is typically between 350 to 473 amino acids in length. This domain is found associated with N1221.
Interpro abstract (IPR021819):

This domain can be found in the C terminus of the yeast Far11 protein and the human STRP1/2 proteins.

Budding yeast Far11 interacts with the phosphatases Pph21, Pph22, and Pph3 and may be involved in the regulation of autophagy and the DNA damage signaling [ (PUBMED:22782902) ]. STRP1/2 (also known as FAM40A/B) are regulators of cytoskeletal organization, cell morphology and migration [ (PUBMED:21834987) ].

Family alignment:
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There are 1679 DUF3402 domains in 1679 proteins in SMART's nrdb database.

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