FeoA

 FeoA
SMART accession number:SM00899
Description: This entry represents the core domain of the ferrous iron (Fe2+) transport protein FeoA found in bacteria. This domain also occurs at the C-terminus in related proteins. The transporter Feo is composed of three proteins: FeoA a small, soluble SH3-domain protein probably located in the cytosol; FeoB, a large protein with a cytosolic N-terminal G-protein domain and a C-terminal integral inner-membrane domain containing two 'Gate' motifs which likely functions as the Fe2+ permease; and FeoC, a small protein apparently functioning as an [Fe-S]-dependent transcriptional repressor. Feo allows the bacterial cell to acquire iron from its environment.
Interpro abstract (IPR007167):

This entry represents the core domain of the ferrous iron (Fe2+) transport protein FeoA found in bacteria. This domain also occurs at the C terminus in related proteins. This suggests that this domain may be metal-binding. In most cases this is likely to be either iron or manganese.

The transporter Feo is composed of three proteins: FeoA a small, soluble SH3-domain protein probably located in the cytosol which is composed of a beta-barrel with two alpha-helices [ (PUBMED:23104801) ]; FeoB, a large protein with a cytosolic N-terminal G-protein domain and a C-terminal integral inner-membrane domain containing two 'Gate' motifs which likely functions as the Fe2+ permease; and FeoC, a small protein apparently functioning as an [Fe-S]-dependent transcriptional repressor [ (PUBMED:8407793) (PUBMED:16718600) ]. Feo allows the bacterial cell to acquire iron from its environment.

GO function:transition metal ion binding (GO:0046914)
Family alignment:
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There are 20657 FeoA domains in 20026 proteins in SMART's nrdb database.

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