Interleukin-7 and interleukin-9 family.
SMART accession number:SM00127
Description: IL-7 is a cytokine that acts as a growth factor for early lymphoid cells of both B- and T-cell lineages. IL-9 is a multifunctional cytokine that, although originally described as a T-cell growth factor, its function in T-cell response remains unclear.
Interpro abstract (IPR001181):

This entry represents interleukin-7 (IL7), it is a hematopoietic growth factor produced by bone marrow stromal cells. It promotes growth of B- and T-cell precursors and functions with IL2 in the activation of mature T-cells [ (PUBMED:2643102) (PUBMED:3259677) ]. IL-7 and IL-7Ralpha bind the gamma-c receptor forming a complex required for the development and homeostasis of T and B cells [ (PUBMED:19141282) ]. Interleukin-7 and Interleukin-9 belong to the same larger family.

GO process:immune response (GO:0006955)
GO component:extracellular region (GO:0005576)
GO function:interleukin-7 receptor binding (GO:0005139), growth factor activity (GO:0008083)
Family alignment:
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There are 56 IL7 domains in 56 proteins in SMART's nrdb database.

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