MltA specific insert domain
SMART accession number:SM00925
Description: This beta barrel domain is found inserted in the MltA a murein degrading transglycosylase enzyme. This domain may be involved in peptidoglycan binding.
Interpro abstract (IPR005300):

Escherichia coli MltA is a membrane-bound lytic transglycosylase comprised of two domains separated by a large groove, where the peptidoglycan strand binds. Domain A is made up of an N-terminal and a C-terminal portion, which correspond to the 3D domain, named for 3 conserved aspartate residues. Domain B is inserted within the linear sequence of domain A [ (PUBMED:16139297) (PUBMED:16618494) (PUBMED:17502382) ].

MltA is a membrane-bound, murein degrading transglycosylase enzyme that plays an important role in the controlled growth of the stress-bearing sacculus of E. coli [ (PUBMED:10037771) (PUBMED:9287002) ].

GO function:hydrolase activity, hydrolyzing O-glycosyl compounds (GO:0004553)
Family alignment:
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There are 6585 MltA domains in 6585 proteins in SMART's nrdb database.

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