This family features sequences that are similar to a region of hypothetical yeast gene product N2227. This is thought to be expressed during meiosis and may be involved in the defence response to stressful conditions PMID:8771715.
This family features sequences that are similar to a region of hypothetical yeast gene product N2227 ( P53934 ). This is thought to be expressed during meiosis and may be involved in the defence response to stressful conditions [ (PUBMED:8771715) ].
Family alignment:
There are 2092 N2227 domains in 2090 proteins in SMART's nrdb database.
Click on the following links for more information.
Evolution (species in which this domain is found)
Taxonomic distribution of proteins containing N2227 domain.
This tree includes only several representative species. The complete taxonomic breakdown of all proteins with N2227 domain is also avaliable.
Click on the protein counts, or double click on taxonomic names to display all proteins containing N2227 domain in the selected taxonomic class.
Literature (relevant references for this domain)
Primary literature is listed below; Automatically-derived, secondary literature is also avaliable.
Sequence analysis of a 14.2 kb fragment of Saccharomyces cerevisiae chromosomeXIV that includes the ypt53, tRNALeu and gsr m2 genes and four new open readingframes.
Yeast. 1996; 12: 599-608
Display abstract
As part of the EU yeast genome program, a fragment of 14,262 bp from the left armof Saccharomyces cerevisiae chromosome XIV has been sequenced. This fragmentcorresponds to cosmid 14-14b and is located roughly 130 kb from the centromere.It contains four new open reading frames which encode potential proteins of more than 99 amino acids, as well as the ypt53, tRNALeu and gsr moffenes. The putativeprotein N2212 is similar to the ribosomal protein S7 from humans. N2215 contains several predicted transmembrane elements. N2231 contains regions which are richin acidic, as well as basic, residues which could from alpha-helical structures. Similar regions are found in a variety of proteins including glutamic acid richprotein, trichohyalin, caldesmon, Tb-29 and several cytoskeleton-interactingproteins.
Links (links to other resources describing this domain)
