Letunic et al. (2017) Nucleic Acids Res doi: 10.1093/nar/gkx922
Letunic et al. (2020) Nucleic Acids Res doi: 10.1093/nar/gkaa937

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NIL

SMART accession number:	SM00930
Description:	This domain is found at the C-terminus of ABC transporter proteins involved in D-methionine transport as well as a number of ferredoxin-like proteins. This domain is likely to act as a substrate binding domain. The domain has been named after a conserved sequence in some members of the family.
Interpro abstract (IPR018449):	This domain is found at the C terminus of ABC transporter proteins involved in D-methionine transport as well as a number of ferredoxin-like proteins. This domain is likely to act as a substrate binding domain. The domain has been named after a conserved sequence in some members of the family.
Family alignment:	View or CHROMA formatHMM/Web logoCLUSTALW formatMSF formatFASTA formatPIR format

There are 13488 NIL domains in 13437 proteins in SMART's nrdb database.

Click on the following links for more information.

• Evolution (species in which this domain is found)

• Taxonomic distribution of proteins containing NIL domain.

  This tree includes only several representative species. The complete taxonomic breakdown of all proteins with NIL domain is also avaliable.

  Click on the protein counts, or double click on taxonomic names to display all proteins containing NIL domain in the selected taxonomic class.

• Cellular role (predicted cellular role)

• Cellular role: transport
  

• Structure (3D structures containing this domain)

• 3D Structures of NIL domains in PDB

  PDB code	Main view	Title
  2qrr		Crystal structure of the soluble domain of the ABC transporter, ATP-binding protein from Vibrio parahaemolyticus
  2qsw		Crystal structure of C-terminal domain of ABC transporter / ATP-binding protein from Enterococcus faecalis
  3ced		Crystal structure of the C-terminal NIL domain of an ABC transporter protein homologue from Staphylococcus aureus
  3dhw		Crystal structure of methionine importer MetNI
  3dhx		Crystal structure of isolated C2 domain of the methionine uptake transporter
  3tui		Inward facing conformations of the MetNI methionine ABC transporter: CY5 native crystal form
  3tuj		Inward facing conformations of the MetNI methionine ABC transporter: DM crystal form
  3tuz		Inward facing conformations of the MetNI methionine ABC transporter: CY5 SeMet soak crystal form

• Links (links to other resources describing this domain)

• PFAM	NIL
  INTERPRO	IPR018449

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