Parathyroid hormone
SMART accession number:SM00087
Description: -
Interpro abstract (IPR001415):

Parathyroid hormone (PTH) is a polypeptidic hormone that elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Parathyroid hormone-related protein (PTH-rP) is structurally related to PTH [ (PUBMED:2682846) ] and seems to play a physiological role in lactation, possibly as a hormone for the mobilisation and/or transfer of calcium to the milk. It also regulates chondrocytic differentiation and endochondral bone formation [ (PUBMED:11760831) ].

PTH and PTH-rP bind to the same G-protein coupled receptor.

This entry represents parathyroid hormone and parathyroid hormone-related protein.

GO component:extracellular region (GO:0005576)
GO function:hormone activity (GO:0005179)
Family alignment:
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There are 346 PTH domains in 345 proteins in SMART's nrdb database.

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