Alpha-macro-globulin thiol-ester bond-forming region
SMART accession number:SM01419
Description: This short highly conserved region of proteinase-binding alpha-macro-globulins contains the cysteine and a glutamine of a thiol-ester bond that is cleaved at the moment of proteinase binding, and mediates the covalent binding of the alpha-macro-globulin to the proteinase. The GCGEQ motif is highly conserved.
Family alignment:
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There are 0 Thiol-ester_cl domains in 0 proteins in SMART's nrdb database.

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  • Structure (3D structures containing this domain)
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