Letunic et al. (2017) Nucleic Acids Res doi: 10.1093/nar/gkx922
Letunic et al. (2020) Nucleic Acids Res doi: 10.1093/nar/gkaa937

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YccV-like Hemimethylated DNA-binding protein YccV like

SMART accession number:	SM00992
Description:	YccV is a hemimethylated DNA binding protein which has been shown to regulate dnaA gene expression. The structure of one of the hypothetical proteins in this family has been solved and it forms a beta sheet structure with a terminating alpha helix.
Interpro abstract (IPR011722):	Heat shock protein HspQ, also known as YccV, is an Escherichia coli hemimethylated DNA binding protein which has been shown to regulate dnaA gene expression [ (PUBMED:12700277) ]. This entry represents a YccV-like hemimethylated DNA binding domain that can also be found in longer eukaryotic proteins.
GO function:	DNA binding (GO:0003677)
Family alignment:	View or CHROMA formatHMM/Web logoCLUSTALW formatMSF formatFASTA formatPIR format

There are 4240 YccV-like domains in 4235 proteins in SMART's nrdb database.

Click on the following links for more information.

• Evolution (species in which this domain is found)

• Taxonomic distribution of proteins containing YccV-like domain.

  This tree includes only several representative species. The complete taxonomic breakdown of all proteins with YccV-like domain is also avaliable.

  Click on the protein counts, or double click on taxonomic names to display all proteins containing YccV-like domain in the selected taxonomic class.

• Cellular role (predicted cellular role)

• Cellular role: chromatin
  

• Structure (3D structures containing this domain)

• 3D Structures of YccV-like domains in PDB

  PDB code	Main view	Title
  1vbv		Crystal structure of hypothetical protein from Esherichia coli

• Links (links to other resources describing this domain)

• INTERPRO	IPR011722
  PFAM	YccV-like

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