Letunic et al. (2017) Nucleic Acids Res doi: 10.1093/nar/gkx922
Letunic et al. (2020) Nucleic Acids Res doi: 10.1093/nar/gkaa937

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CG-1

SMART accession number:	SM01076
Description:	CG-1 domains are highly conserved domains of about 130 amino-acid residues containing a predicted bipartite NLS and named after a partial cDNA clone isolated from parsley encoding a sequence-specific DNA-binding protein (PUBMED:8075408). CG-1 domains are associated with CAMTA proteins (for CAlModulin -binding Transcription Activator) that are transcription factors containing a calmodulin -binding domain and ankyrins (ANK) motifs (PUBMED:11925432).
Interpro abstract (IPR005559):	CG-1 domains are highly conserved domains of about 130 amino-acid residues containing a predicted bipartite nuclear localisation signal. They are named after a partial cDNA clone isolated from parsley encoding a sequence-specific DNA-binding protein [ (PUBMED:8075408) ]. CG-1 domains are found in CAMTA proteins (for CAlModulin -binding Transcription Activator), which are transcription factors containing a calmodulin-binding domain and ankyrin repeats [ (PUBMED:11925432) ].
GO function:	DNA binding (GO:0003677)
Family alignment:	View or CHROMA formatHMM/Web logoCLUSTALW formatMSF formatFASTA formatPIR format

There are 2235 CG-1 domains in 2230 proteins in SMART's nrdb database.

Click on the following links for more information.

• Evolution (species in which this domain is found)

• Taxonomic distribution of proteins containing CG-1 domain.

  This tree includes only several representative species. The complete taxonomic breakdown of all proteins with CG-1 domain is also avaliable.

  Click on the protein counts, or double click on taxonomic names to display all proteins containing CG-1 domain in the selected taxonomic class.

• Cellular role (predicted cellular role)

• Cellular role: transcription
  

• Literature (relevant references for this domain)

• Primary literature is listed below; Automatically-derived, secondary literature is also avaliable.

  • da Costa e Silva O
  • CG-1, a parsley light-induced DNA-binding protein.
  • Plant Mol Biol. 1994; 25: 921-4
  • Display abstract

  • A partial cDNA clone (CG-1) encoding a sequence-specific DNA-bindingprotein (CG-1) was isolated from a parsley (Petroselinum crispum L.) cDNAexpression library by a DNA-ligand screening. The nucleotide sequence CGCGis a required motif in this protein's binding site. Interestingly, themRNA coding for CG-1 accumulated rapidly and transiently in parsleycultured cells after treatment with UV-containing white light. Althoughthe target gene(s) for CG-1 has not been identified, its sequence-specificDNA binding and expression pattern, make CG-1 a possible member of a lightsignal transduction chain in parsley.

• Links (links to other resources describing this domain)

• INTERPRO	IPR005559
  PFAM	CG-1

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